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Moumoujus

CALOPHYLLUM INOPHYLLUM SEED OIL.

Valuable CAS - / ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, ORAL CARE, SKIN CONDITIONING, UV ABSORBER

Commonly known as Tamanu oil, this potent botanical lipid is a high-performance regenerative agent prized for its unique ability to accelerate tissue repair and diminish the appearance of established scars. It serves as a multi-functional therapeutic oil that bridges the gap between traditional ethnomedicine and modern precision skincare.

Summary

antioxidant emollient antimicrobial skin-regenerating anti-inflammatory

Science

Mechanism of Action

This oil functions by stimulating fibroblast proliferation and cell renewal, which significantly enhances the synthesis of collagen and glycosaminoglycans (GAGs). It exerts a localized anti-inflammatory effect by inhibiting pro-inflammatory cytokines like IL-1b and TNF-a while promoting M2 macrophage polarization; additionally, its unique bioactive markers, calophyllolide and calophyllic acid, provide innate antimicrobial and antifungal properties.

Research

Clinical Evidence

High confidence
Effective range 0.1–100%
Optimal

7.31%

Key findings

  1. 01 In vitro scratch assays revealed that concentrations as low as 0.1% can accelerate wound closure by factors 1.3 to 2.1 times higher than untreated controls.
  2. 02 Topical application at 100% concentration demonstrated visible reduction in the appearance and texture of scars older than one year over a 6 to 9-week period.
  3. 03 Advanced nanoemulsion formulations at 7.31% have been shown to optimize fibroblast migration and cellular viability for enhanced barrier recovery.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Because clinical efficacy in wound closure is observed at levels as low as 0.1%, it is difficult to classify this as 'dusted' if present at measurable amounts; however, marketing-led formulations may include it below 0.05% purely for label claims.

The Formula

Formulation

Solubility
Oil
Optimal pH 5.5 – 6.5
0 7 14

Stability

Highly susceptible to oxidative rancidity due to a high polyunsaturated fatty acid profile. Formulations must be stabilized with antioxidants, stored at room temperature, and protected from UV light to prevent degradation.

Synergies

  • Vitamin E (Tocopherol) for oxidative stability
  • Ceramides for enhanced barrier repair
  • Linoleic acid-rich oils

Conflicts

  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Safe as used
Max tested
100%
Pregnancy
Safe
Sensitization risk Low

Generally non-sensitizing and non-irritating; however, the oil must be fresh and properly stabilized, as oxidized oils can cause skin reactivity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptional bioactive lipid for regenerative and anti-inflammatory applications, backed by strong evidence for scar reduction and cellular repair.

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