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Ingredient directory

Calocedrus Formosana Leaf Extract

A high-performance botanical extract derived from the Taiwan Incense Cedar, engineered to address the dual concerns of microbial congestion and enzymatic hyperpigmentation. This precision ingredient stabilizes the skin environment by neutralizing oxidative stress and inhibiting the biological triggers of blemish formation.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

antioxidant skin brightening anti-acne soothing antimicrobial

Science

Mechanism of Action

This extract employs a multi-targeted pathway: it downregulates melanogenesis-related proteins (MITF, TRP-1, and TRP-2) to block pigment synthesis and acts as a potent tyrosinase inhibitor. Simultaneously, it exerts significant antimicrobial pressure on Cutibacterium acnes while providing radical scavenging protection via superoxide anion and DPPH neutralization.

Research

Clinical Evidence

High confidence
Effective range 0.1–5%
Optimal

5%

Key findings

  1. 01 In vivo clinical testing demonstrated a 7.8% reduction in active acne lesions over a 30-day period.
  2. 02 In vitro analysis confirmed a 99.9% growth inhibition of Propionibacterium acnes.
  3. 03 Tyrosinase inhibition studies yielded a highly potent IC50 of 2.72 μg/mL, indicating superior brightening potential.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

With documented efficacy starting at 0.1% for antimicrobial action and clinical visible results at 1-5%, concentrations below 0.1% are likely insufficient for therapeutic benefits beyond basic antioxidant support.

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 6.5
0 7 14

Stability

The extract is stable at room temperature but exhibits sensitivity to ultraviolet radiation and thermal degradation; amber glass or opaque packaging is mandatory.

Synergies

  • Niacinamide
  • Vitamin C derivatives
  • Azelaic Acid
  • Hyaluronic Acid

Conflicts

  • Strong oxidizing agents
  • Excessive heat during emulsification

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

Validated as non-irritating and non-sensitizing through OECD 439 and 442C standardized alternative testing protocols.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptional multi-functional botanical for precision skincare, offering scientifically-backed results for both acne management and skin tone uniformity.

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