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CALLISTEPHUS CHINENSIS LEAF EXTRACT.

Valuable / SKIN CONDITIONING

Derived from the China Aster, this botanical extract serves as a multi-functional phyto-active that focuses on DNA protection and inflammatory modulation. It is particularly rich in anthocyanins and flavonoids, providing a robust defense against oxidative stress and environmental photo-damage.

antioxidant anti-inflammatory skin-brightening dna-protection

Science

This extract operates through a high concentration of pelargonidin 3-O-glucoside and phenolic compounds to neutralize reactive oxygen species (ROS) before they can trigger cellular damage. It further regulates the skin's inflammatory response by inhibiting the TLR-4 and NF-κB pathways, effectively suppressing pro-inflammatory cytokines like IL-6 and IL-17 while simultaneously mitigating melanin synthesis through tyrosinase inhibition.


Research

High confidence
Effective range 0.01–10%
Optimal

0.1%

Key findings

  1. 01 Demonstrated significant preservation of DNA integrity against UV-induced hydroxyl radicals at 0.1% concentration.
  2. 02 Shown to inhibit melanin production and provide brightening effects in concentrations ranging from 0.01% to 10%.
  3. 03 Exhibited anti-psoriatic and systemic anti-inflammatory benefits in vivo by reducing PASI scores and suppressing TLR-4 expression.

Transparency

Commonly dusted
Min. effective
0.05%
Red flag below
0.01%

Because botanical extracts are often marketed for their 'natural' appeal, this ingredient is frequently included at trace amounts (below 0.01%) for label claims. However, clinical data suggests DNA protection and tyrosinase inhibition require at least 0.1% for measurable efficacy.


The Formula

Solubility
Water
Optimal pH 4 – 5.5
0 7 14

Stability

Highly sensitive to alkaline environments and thermal degradation. Anthocyanin stability is best maintained in slightly acidic conditions; pH levels above 6.0 may cause a bathochromic color shift and reduced antioxidant potency.

Synergies

  • Vitamin C
  • Niacinamide
  • Soothing peptides

Conflicts

  • Strong oxidizing agents
  • Highly alkaline ingredients
  • Ferric ions

Safety

CIR Status
Not reviewed by CIR
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Listed as a safe skin-conditioning agent in the EU CosIng database. No reported acute toxicity or sensitization at standard formulation levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical that offers scientifically-backed DNA protection and brightening benefits when formulated within a precise acidic pH range.


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