Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

CALLIANDRA PORTORICENSIS SYMBIOSOME EXTRACT.

Valuable CAS - / SKIN CONDITIONING

A sophisticated botanical bioactive derived from nitrogen-fixing root nodules that functions as a high-performance cellular revitalizer. It is specifically engineered to bolster the skin's structural integrity by targeting longevity pathways typically diminished by chronological aging and environmental stress.

SIRT1 activation Skin conditioning Anti-aging DNA repair support

Science

This extract operates as a potent Sirtuin 1 (SIRT1) activator, upregulating the 'longevity proteins' responsible for DNA repair and cellular resilience. By enhancing mitochondrial energy efficiency and reducing oxidative markers, it creates an optimal environment for the synthesis of essential structural proteins like collagen and elastin.


Research

High confidence
Effective range 0.1–5%
Optimal

1%

Key findings

  1. 01 In-vitro fibroblast analysis demonstrated significant SIRT1 expression stimulation at concentrations as low as 0.1%, facilitating enhanced cellular repair.
  2. 02 Clinical evaluation of an anti-aging complex containing 1.0%–5.0% of the extract showed measurable gains in skin firmness and a visible reduction in fine lines over an 8-week period.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.5%

Because this ingredient is effective in-vitro at very low levels (0.1%), many brands include it at 'label claim' concentrations. To achieve the firming results seen in clinical consumer trials, a concentration of at least 1.0% is recommended.


The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Thermolabile; must be incorporated during the cool-down phase below 40°C to maintain bioactivity. Highly stable in standard aqueous systems and emulsions.

Synergies

  • Peptides
  • Niacinamide
  • Hyaluronic Acid

Conflicts

  • Strong oxidizing agents
  • High electrolyte concentrations
  • Extreme pH environments (<4.0 or >7.5)

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Derived from the Fabaceae family; utilized extensively by premium dermatological brands with a proven safety profile in topical applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A precision-engineered botanical that bridges the gap between nature and molecular biology to effectively target the root causes of skin laxity.


Related

Finding similar ingredients…