Science
Mechanism of Action
Operates via high-bioavailability signaling molecules, specifically EGF, VEGF, and PDGF, which dock onto cell receptors to activate fibroblast proliferation. This process triggers the synthesis of new collagen and hyaluronic acid while simultaneously restoring the lipid barrier through its natural refatting properties.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Demonstrated biostimulation of the extracellular matrix, significantly increasing structural proteins and glycosaminoglycans for enhanced elasticity.
- 02 Proven efficacy in 45-day trials as a transdermal facilitator, reducing wrinkle depth by improving the delivery of high-molecular-weight actives.
Transparency
Dusting Analysis
Due to its high cost and complex sourcing, many formulations include it at 'label claim' levels below 0.5%, which is insufficient to trigger the growth factor pathways identified in clinical patents.
The Formula
Formulation
Stability
Thermally labile; biological activity degrades rapidly if exposed to temperatures exceeding 50°C. Requires precise pH control to prevent protein denaturation.
Synergies
- Hyaluronic Acid
- Non-proteolytic peptides
- Ceramides
Conflicts
- Strong acids (AHA/BHA)
- Proteolytic enzymes
- Heavy metals
- High heat processing
Safety
Safety Profile
Must be sourced from certified BSE-free regions and comply with FDA 21 CFR 700.27 and EU Annex II regulations regarding bovine-derived materials.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A potent bio-active for age reversal and barrier repair, provided it is formulated cold and used at therapeutic concentrations.
Related
Similar Ingredients
Finding similar ingredients…