Science
Mechanism of Action
This ingredient functions via a triple-action pathway: it forms a non-occlusive film that prevents trans-epidermal water loss (TEWL), inhibits the hyaluronidase enzyme to protect endogenous hyaluronic acid, and bio-stimulates the production of Natural Moisturizing Factors (NMFs) including lactic acid and PCA.
Research
Clinical Evidence
High confidence0.5%
Key findings
- 01 A 1.0% concentration demonstrated a 172% surge in hydration levels and a 43% reduction in moisture loss within one hour of application.
- 02 8-week longitudinal data shows a 122% improvement in skin elasticity and a 34% reduction in visible wrinkle depth.
- 03 Clinical evidence suggests a 39% reduction in pore visibility and a 49% increase in skin firmness at active concentrations.
Transparency
Dusting Analysis
While many formulas include this for 'label appeal' at trace amounts, clinical benchmarks for significant elasticity and hydration improvements require a minimum threshold of 0.1%.
The Formula
Formulation
Stability
Maintains peak stability at a neutral pH of 6.5–7.0. Formulations must stay above pH 4.0 to prevent the polymer from precipitating into polyglutamic acid.
Synergies
- Hyaluronic Acid
- Glycerin
- NMF components (Lactic Acid, PCA)
Conflicts
- Cationic surfactants
- Polyquaterniums
- High concentrations of divalent cations
- Strong oxidizing agents
Safety
Safety Profile
Classified as safe by the 2022 CIR assessment. It is non-irritating and suitable for long-term use in leave-on applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An elite hydrating agent that provides immediate surface smoothing while actively preserving the skin's long-term moisture reserves.
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References
Sources