Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

CALCIUM DNA.

Valuable / SKIN CONDITIONING

A high-performance bio-mineral complex that utilizes the structural stability of calcium to deliver nucleic acid fragments to the skin. This sophisticated ingredient acts as both a biological humectant and a surface-conditioning agent to enhance cellular vitality and moisture retention.

Skin conditioning Humectant Moisturizing Texture improvement

Science

The calcium ion serves as a stabilizer for the DNA molecule, facilitating electrostatic adsorption to the skin's surface. Once applied, it functions as a powerful humectant by binding water molecules within the extracellular matrix and delivering essential minerals and nucleic acid fragments that support natural regenerative functions.


Research

High confidence
Effective range 0.5–1%
Optimal

0.75%

Key findings

  1. 01 In-vitro models demonstrate that specialized DNA complexes can retain up to 10,000 times their weight in water.
  2. 02 Clinical benchmarks at 0.5-1.0% concentrations show significant improvements in skin texture and surface-level hydration.

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Due to its high raw material cost and marketing appeal in luxury 'DNA-repair' categories, it is frequently included at concentrations below 0.1%, which is insufficient for meaningful physiological impact.


The Formula

Solubility
Water
Optimal pH 5.5 – 7.5
0 7 14

Stability

Thermolabile; the DNA structure degrades at high temperatures and must be incorporated during the cool-down phase of production.

Synergies

  • Hyaluronic Acid
  • Magnesium PCA
  • Nucleotides

Conflicts

  • High concentrations of phosphate ions
  • Alkaline environments (pH > 8.0)
  • Anionic surfactants

Safety

CIR Status
Not reviewed
Max tested
1%
Pregnancy
Safe
Sensitization risk Low

Generally regarded as safe (GRAS) and highly biocompatible; it is well-tolerated in long-term clinical applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional biological humectant for precision hydration and texture refinement, provided it is used at concentrations above 0.5%.


Related

Finding similar ingredients…