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CALAMINTHA OFFICINALIS FLOWER/LEAF/STEM EXTRACT.

Valuable CAS 223748-11-6 / SKIN CONDITIONING

A multifaceted botanical extract derived from Lesser Calamint, specifically utilized for its high concentration of bioactive monoterpenes and antioxidant enzymes. It functions as both a skin-conditioning agent and a natural auxiliary preservative, helping to maintain formula integrity while soothing reactive skin.

Antioxidant Antimicrobial Skin Conditioning Soothing

Science

The extract functions via a dual-action pathway: it neutralizes oxidative stress by scavenging superoxide anion radicals through enzymatic activity (SOD and CAT mimicry) and disrupts microbial cell membranes using its natural monoterpene profile—specifically carvone, pulegone, and trans-caryophyllene. Additionally, it enhances the skin's barrier by improving moisture retention and suppressing inflammatory markers that cause surface redness.


Research

Medium confidence
Effective range 1–2%
Optimal

1.5%

Key findings

  1. 01 Nostro, A., et al. (2010) demonstrated that at 1.0-2.0%, the extract provides effective antimicrobial activity satisfying European Pharmacopoeia standards.
  2. 02 Moattar, F. S., et al. (2018) confirmed significant antioxidant enzymatic power, specifically in protecting against superoxide anion-induced oxidative stress.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

This ingredient is frequently used at 'label claim' levels (below 0.1%) to market a botanical profile. However, clinical data suggests that concentrations of at least 1.0% are required to achieve its documented antimicrobial and significant antioxidant benefits.


The Formula

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

Highly prone to photo-oxidation and degradation. It requires stabilization with chelating agents or antioxidants like citric acid and must be stored in light-protected packaging.

Synergies

  • Vitamin E
  • Chelating agents (EDTA, Sodium Phytate)
  • Glycerin

Conflicts

  • Strong oxidizing agents
  • Highly alkaline environments (pH > 8.0)

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

While generally safe, the extract contains pulegone, which is subject to specific concentration limits in some regions if used as a fragrance component.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An excellent botanical choice for formulations targeting oxidative stress and microbial balance, provided it is used at high enough concentrations to be effective.


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