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CAFFEINE CARBOXYLIC ACID.

Valuable CAS 652-37-9 / SKIN CONDITIONING

A sophisticated derivative of traditional caffeine designed for enhanced stability and precision delivery in topical applications. This multifunctional molecule excels at optimizing microcirculation and reducing localized fluid retention, making it a premier choice for refining skin texture and eye area contours.

Microcirculation stimulant Lipolytic agent Skin conditioning Masking agent Solvent

Science

It functions as a vasotonic agent, stimulating skin microcirculation to alleviate congestion and under-eye puffiness. Furthermore, it encourages lipolysis to help minimize localized fat deposits while simultaneously acting as a skin-conditioning agent to improve surface smoothness.


Research

High confidence
Effective range 0.5–1.2%
Optimal

1%

Key findings

  1. 01 Concentrations between 0.5% and 1.2% have demonstrated significant efficacy in reducing periocular swelling and improving overall skin hydration.
  2. 02 Clinical data indicates that at a 1.0% concentration, the ingredient provides a prolonged release of active principles, aiding in the firming and reshaping of body and facial contours.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

With established efficacy starting as low as 0.5%, formulations containing less than this amount may only be utilizing the ingredient for its solvent or masking properties rather than its active depuffing and lipolytic benefits.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Exhibits high stability within aqueous systems and emulsions; it maintains structural integrity across a broad pH spectrum.

Synergies

  • Active ingredients requiring high-stability solvents
  • Hydrating agents
  • Other microcirculation boosters

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Recognized by the European Commission's CosIng database as a safe skin-conditioning and masking agent without specific concentration restrictions.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally stable and versatile active for addressing fluid retention and congestion with a superior safety profile for all skin types.


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