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CAFFEIC ACID.

Valuable CAS 331-39-5 / ANTIOXIDANT, FRAGRANCE

A potent phenolic phytochemical naturally found in coffee and various plants, Caffeic Acid serves as a multifunctional bioactive that bridges the gap between environmental defense and structural repair. It is highly regarded for its ability to shield skin from UV-induced oxidative stress while simultaneously addressing hyperpigmentation and early signs of aging.

antioxidant brightening anti-inflammatory photoprotective adjuvant collagen protection

Science

This ingredient operates as a robust electron donor to neutralize reactive oxygen species (ROS) and inhibit lipid peroxidation. Beyond surface protection, it regulates melanogenesis by inhibiting tyrosinase enzymes and exerts an anti-inflammatory effect by downregulating specific signaling pathways like NF-κB and MAPK, while concurrently supporting collagen integrity and DNA repair mechanisms.


Research

High confidence
Effective range 0.1–2%
Optimal

0.5%

Key findings

  1. 01 Demonstrated measurable photoprotection and ROS scavenging against UV-induced erythema.
  2. 02 High epidermal and dermal retention achieved with minimal systemic absorption, optimizing localized antioxidant activity.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Because Caffeic Acid shows biological activity even at very low concentrations (0.1%), many brands include it at trace amounts for marketing claims. For significant antioxidant and brightening results, concentrations between 0.2% and 2.0% are required.


The Formula

Solubility
Both
Optimal pH 4.5 – 6
0 7 14

Stability

Highly prone to oxidation and photodegradation; must be stored in opaque, airtight packaging. It displays better solubility in glycols like propanediol or hot water than cold water.

Synergies

  • Ferulic Acid
  • Vitamin C (Ascorbic Acid)
  • Vitamin E
  • Broad-spectrum Sunscreens

Conflicts

  • Strong oxidizing agents
  • Iron salts
  • Alkaline formulations (pH > 7.0)

Safety

CIR Status
Not reviewed
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

While IARC 2B and Prop 65 listings exist regarding high-dose oral ingestion, topical application at cosmetic levels (up to 2%) is considered safe due to low systemic permeation.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance antioxidant and brightening agent that significantly enhances skin's resilience against environmental damage when formulated correctly.


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