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C21-28 ALKANE.

Valuable CAS 64742-55-8 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

A high-purity, biodegradable hydrocarbon blend that serves as a sophisticated alternative to traditional silicones. This inert emollient provides a weightless, non-greasy finish while significantly enhancing the structural integrity and spreadability of advanced topical delivery systems.

Emollient Occlusive Viscosity Controller Skin Conditioner

Science

This non-polar saturated hydrocarbon creates a breathable, hydrophobic barrier on the skin's surface. By forming this thin occlusive film, it physically prevents transepidermal water loss (TEWL) and integrates into the intercellular spaces of the stratum corneum to smooth texture and restore barrier lipid functionality.


Research

High confidence
Effective range 1–47.6%
Optimal

5%

Key findings

  1. 01 In vivo testing at 1-5% concentrations demonstrated a measurable reduction in TEWL and a significant increase in cutaneous hydration over a 28-day period.
  2. 02 Comparative rheological studies show that at 2%, this ingredient provides superior emulsion stability and more uniform droplet distribution than isohexadecane.
  3. 03 High-concentration microemulsion research indicates the alkane achieves exceptional skin adhesion and spreadability without leaving a heavy or oily residue.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

While often used as a functional texture enhancer, its clinical benefits for barrier repair are realized at levels between 1% and 5%. Formulations containing less than 1% may be utilizing it solely for solvent properties rather than skin-replenishing benefits.


The Formula

Solubility
Oil
Optimal pH 2 – 12
0 7 14

Stability

Highly resilient and chemically inert; it remains stable against oxidation, UV exposure, and extreme pH fluctuations. It is universally compatible with vegetable oils, synthetic esters, and silicones.

Synergies

  • Lipophilic active ingredients
  • Mineral UV filters
  • Ceramides

Safety

CIR Status
Safe as used
Max tested
100%
Pregnancy
Safe
Sensitization risk Low

Classified as high-purity and readily biodegradable, it is free from volatile aromatics and heavy metals, making it an eco-conscious choice for sensitive skin formulations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A precision-engineered emollient that bridges the gap between high-performance skin hydration and elegant cosmetic aesthetics.


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