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C18-50 ISOPARAFFIN.

Valuable

A high-performance synthetic hydrocarbon that serves as a protective occlusive and skin-conditioning agent. It is valued in precision skincare for creating a resilient, breathable moisture barrier without the greasy residue associated with traditional heavy waxes.

Emollient Occlusive Solvent Skin Conditioning Agent

Science

This ingredient functions as a superior occlusive emollient. Due to its high molecular weight and branched-chain architecture, it forms a hydrophobic film on the skin's surface, effectively locking in moisture and preventing transepidermal water loss (TEWL) without penetrating the deeper layers of the stratum corneum.


Research

High confidence
Effective range 0.0001–90%
Optimal

N/A

Key findings

  1. 01 Human patch testing conducted on 100% undiluted mixtures (C18-70 range) confirmed the substance is non-irritating and non-sensitizing over 48-hour exposure periods.
  2. 02 Safety evaluations published in the International Journal of Toxicology support its use as a systemic-safe solvent and emollient, citing its bulky molecular size as a deterrent to significant skin absorption.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.1%

Because it is often used as a functional solvent or texture enhancer, concentrations below 1% in moisturizers may be insufficient to provide meaningful occlusive benefits, though it is rarely used in 'marketing-only' amounts.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Extremely chemically inert and resistant to photo-oxidation, temperature fluctuations, and discoloration. It maintains stability across a wide environmental range and does not impact formula pH.

Synergies

  • Humectants (to seal in moisture)
  • Lipophilic active ingredients

Conflicts

  • Water-based systems (requires emulsification)
  • Highly polar solvents

Safety

CIR Status
Safe as used
Max tested
90%
Pregnancy
Safe
Sensitization risk Low

Recognized as safe for cosmetic use by the CIR Expert Panel and approved by the FDA for use in direct food contact coatings, underscoring its high biocompatibility.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally stable and non-sensitizing barrier-supporting agent that provides significant hydration benefits for dry and compromised skin types.


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References