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C14-16 GLYCOL PALMITATE.

Valuable CAS 246159-40-0 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

A multifunctional fatty acid ester that serves as both a high-performance emollient and a secondary emulsifier. It is primarily utilized to enhance the structural integrity and application aesthetics of precision skincare formulations, providing a smooth, non-streaking finish.

emollient co-emulsifier skin conditioning agent opacifying agent thickener

Science

This non-ionic ingredient utilizes a dual-nature molecular structure—a lipophilic palmitic chain and a hydrophilic glycol component—to stabilize oil-water interfaces. On the stratum corneum, it acts as a biomimetic lipid, integrating into the gaps between skin cells to reinforce the moisture barrier and significantly reduce transepidermal water loss.


Research

High confidence
Effective range 0.1–5%
Optimal

2%

Key findings

  1. 01 Demonstrated efficacy at 1.0-3.0% for eliminating the 'soaping effect' and improving the sensory profile of emulsions.
  2. 02 Identified as a texture enhancer and opacifier in surfactant systems within the 0.1-5.0% range without disrupting foam mechanics.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.1%

While functional as an opacifier at very low levels (0.1%), its primary benefits for skin barrier support and emulsion stabilization require concentrations above 1.0%. Products claiming 'barrier repair' using this ingredient at sub-1% levels may be under-dosing for marketing purposes.


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Highly stable within the physiological pH range; however, it is prone to hydrolysis and saponification if exposed to extreme pH environments (below 3.0 or above 9.0).

Synergies

  • Primary emulsifiers
  • Lipid-replenishing actives
  • Surfactant blends

Conflicts

  • Strong oxidizing agents
  • Strong mineral acids
  • Strong alkaline bases

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Classified within the Alkyl Esters group; recognized for its excellent safety profile in leave-on applications up to 10% concentration.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An excellent supporting ingredient for stabilizing sophisticated emulsions while providing essential lipid-barrier replenishment for all skin types.


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