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C12-15 PARETH-2 PHOSPHATE.

Valuable CAS 68071-35-2 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A sophisticated anionic surfactant and emulsifying agent that facilitates the creation of stable, lightweight emulsions. It is prized in high-performance skincare for its skin-mimetic properties and its ability to enhance the delivery of active molecules without leaving a greasy residue.

Emulsifying Surfactant Cleansing Penetration Enhancer

Science

As a phosphate ester, it reduces interfacial tension between oil and water phases to form stable emulsions. Its molecular structure resembles the natural phospholipids found in the stratum corneum, allowing it to integrate seamlessly into the skin's lipid barrier to improve ingredient penetration and provide a silk-like finish.


Research

High confidence
Effective range 0.5–5%
Optimal

2%

Key findings

  1. 01 Dermatological patent data indicates its efficacy in stabilizing high-potency formulations containing Niacinamide and Vitamin C (SAP) while preserving barrier integrity.
  2. 02 Human Repeat Insult Patch Testing (HRIPT) confirms it is non-sensitizing at typical usage levels when properly neutralized.

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Because it serves a structural role in the emulsion, it is rarely 'dusted' for marketing; however, concentrations below 0.5% may indicate it is being used merely as a co-surfactant rather than a primary emulsifier or penetration enhancer.


The Formula

Solubility
Both
Optimal pH 6.5 – 8
0 7 14

Stability

Displays lipophilic characteristics (HLB ~6.5) but becomes water-dispersible upon alkali neutralization. It is prone to hydrolysis in acidic environments below pH 4.0.

Synergies

  • Niacinamide
  • Sodium Ascorbyl Phosphate
  • Lipids

Conflicts

  • Cationic surfactants
  • Strongly acidic environments
  • Polyvalent metal ions

Safety

CIR Status
Safe as used
Max tested
8.3%
Pregnancy
Safe
Sensitization risk Low

Safe for cosmetic use when formulated to be non-irritating; maximum concentration is based on comparative data for related alkyl phosphates.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional emulsifier for precision formulations that require a lightweight feel and enhanced active ingredient delivery.


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References