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C12-13 PARETH-3.

Valuable CAS 66455-14-9 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A non-ionic surfactant and lipophilic emulsifier that stabilizes oil-water interfaces in skincare formulations. With its low HLB value of approximately 8.0, it functions as an effective dispersing agent and spreading enhancer that improves product texture without significant skin barrier disruption.

emulsifying surfactant cleansing dispersing

Science

Reduces interfacial tension between oil and water phases through its amphiphilic structure, enabling stable emulsion formation while acting as a wetting agent for pigments and enhancing the spreadability of topical formulations


Research

Medium confidence
Effective range 0.125–0.45%
Optimal

0.125%

Key findings

  1. 01 Maximum safe concentration established for topical medicines to minimize irritation potential
  2. 02 Effective as co-emulsifier in foaming cleansers without compromising skin barrier function

Transparency

Not commonly dusted

Used as a functional emulsifier and surfactant rather than an active ingredient, making dusting unlikely in skincare formulations


The Formula

Solubility
Oil
Optimal pH 3 – 11
0 7 14

Stability

Demonstrates excellent chemical stability across wide pH range due to stable ether linkage structure

Synergies

  • anionic surfactants
  • cationic surfactants
  • other non-ionic surfactants

Conflicts

  • N-nitrosating agents
  • strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
0.125%
Sensitization risk Low

CIR Expert Panel 2013 confirmed safety when formulated to be non-irritating. Pure material poses eye irritation risk and aquatic toxicity concerns.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-tolerated emulsifying agent that enhances formulation stability and texture across all skin types when used within established concentration limits.


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