Science
Mechanism of Action
Works by filling intercellular spaces to create a smooth skin surface while reducing transepidermal water loss. Additionally enhances the penetration of other actives by increasing their solubility within both the formulation and the lipid layers of the stratum corneum.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated significant enhancement of drug permeation through skin, with penetration rates directly correlating to increased solubility of test compounds in the ester vehicle
Transparency
Dusting Analysis
Not typically used in dusting concentrations as it serves functional roles as emollient and penetration enhancer at meaningful percentages
The Formula
Formulation
Stability
Maintains stability under standard ambient conditions but undergoes hydrolysis at extreme pH levels, breaking down into constituent alcohol and 2-ethylhexanoic acid
Synergies
- UV filters (acts as solubilizer)
- Other lipophilic actives
Conflicts
- Strong oxidizing agents
- Strong acids and bases
- Extreme pH formulations
Safety
Safety Profile
CIR Expert Panel concluded safety when formulated to be non-irritating, with related esters in this family approved at concentrations up to 77% in rinse-off products
Your Skin
Skin Compatibility
Our Assessment
Verdict
A multifunctional ingredient that delivers both immediate skin conditioning benefits and enhanced delivery of other actives with excellent safety profile.
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