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Ingredient directory

C10-40 Isoalkyl Acid Octyldodecanol Esters

A sophisticated ester complex engineered to replicate the branched-chain fatty acid structure naturally found in skin's lipid barrier and lanolin. This high-performance emollient delivers advanced skin conditioning while functioning as a structural enhancer in formulations, making it particularly valuable for barrier repair applications.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

emollient viscosity controlling skin conditioning

Science

Integrates into the lipid matrix between corneocytes, mimicking natural iso-acids to strengthen barrier function and reduce transepidermal water loss. Simultaneously restores skin elasticity and provides non-aqueous viscosity enhancement for improved formulation stability.


Research

High confidence
Effective range 1.5–58%
Optimal

5%

Key findings

  1. 01 Human Repeat Insult Patch Testing at 1.5% demonstrated zero sensitization in 150+ subjects
  2. 02 Comedogenicity testing at 100% concentration showed non-comedogenic properties in rabbit ear assays
  3. 03 Human cumulative irritation studies at 15-58% concentrations classified as minimally irritating

Transparency

Not commonly dusted

Well-established emollient with clear safety data and specific concentration guidelines from CIR assessment


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Exceptionally stable in standard cosmetic matrices, but susceptible to hydrolysis under extreme pH conditions outside 3-9 range

Conflicts

  • Strong oxidizing agents
  • Strongly acidic or alkaline environments (pH <3 or >9)
  • Cationic surfactants in high-electrolyte systems

Safety

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

CIR Expert Panel 2013 assessment confirms safety when formulated appropriately. Higher concentrations permitted in rinse-off and decorative products.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically-backed emollient that delivers both skin benefits and formulation advantages with excellent safety credentials across all skin types.


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