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C10-40 ISOALKYL ACID GLYCERIDE.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A sophisticated biomimetic emollient that delivers branched iso-fatty acids to restore the skin's natural lipid architecture. This glyceride ester enhances barrier function by integrating into intercellular lipid layers, reducing water loss while improving active ingredient penetration. Particularly effective for compromised or mature skin requiring structural lipid replenishment.

emollient skin conditioning barrier repair penetration enhancer occlusive agent

Science

Provides branched C10-40 iso-fatty acids that structurally mimic the skin's natural 18-MEA lipids, integrating into intercellular lipid lamellae to restore barrier integrity, reduce transepidermal water loss, and create lipid pathways that enhance active ingredient delivery into the stratum corneum


Research

Medium confidence
Effective range 0.5–10%
Optimal

2.5%

Key findings

  1. 01 Enhanced penetration system efficacy at 0.5-5% concentration, improving active delivery by mimicking lipid matrix structure
  2. 02 Significant barrier repair and TEWL reduction at 1-10% through iso-fatty acid replenishment

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.1%

Functional concentrations begin at 0.5% for penetration enhancement, with meaningful barrier repair requiring 1%+ levels; sub-1% usage likely represents token inclusion


The Formula

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Excellent stability in anhydrous and standard emulsion systems; vulnerable to hydrolysis below pH 3.0 or above pH 8.0, especially under heat

Synergies

  • ceramides
  • cholesterol
  • other barrier lipids

Conflicts

  • strong oxidizing agents
  • highly alkaline ingredients

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

CIR-assessed as part of triglycerides and glyceryl esters groups in 2017, deemed safe when formulated to avoid irritation


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically sophisticated barrier-repair ingredient that delivers targeted lipid restoration for compromised or aging skin when used at meaningful concentrations.


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