Science
Mechanism of Action
Functions as a SNARE complex inhibitor, breaking down Syntaxin and SNAP-25 proteins in nerve terminals to prevent acetylcholine vesicle fusion and subsequent neurotransmitter release, effectively reducing muscle contractions that form expression lines
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Ex-vivo models demonstrated 88% reduction in muscle contraction within 15 minutes at 1-10% concentration
- 02 4-week clinical trial showed 16% improvement in skin surface roughness and 45% enhancement in microcirculation
- 03 Immediate lifting effects observed within 30 minutes at 5% concentration with sustained wrinkle mitigation
Transparency
Dusting Analysis
Given the specific 1-10% effective concentration range and immediate measurable effects, concentrations below 1% likely represent cosmetic dusting rather than therapeutic dosing
The Formula
Formulation
Stability
Heat-sensitive peptide requiring cool-phase incorporation below 40°C; supplied as liquid dispersion
Conflicts
- Proteolytic enzymes
- Formulations below pH 4.0
- Strong oxidizing agents
Safety
Safety Profile
Synthetic human-identical sequence produced via biotechnology; not restricted under EU cosmetic regulations
Your Skin
Skin Compatibility
Our Assessment
Verdict
Well-researched peptide with quantifiable anti-wrinkle efficacy and broad skin compatibility, though premium pricing may limit accessibility.
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References
Sources