Science
Mechanism of Action
Reinforces skin barrier integrity by upregulating SPINK5 protease inhibitor while downregulating KLK6/KLK13 desquamation enzymes, preventing premature cell shedding. Dose-dependently reduces sebaceous lipid synthesis for oil control and enhances microcirculation while providing antioxidant protection via Nrf2 pathway activation.
Research
Clinical Evidence
Medium confidence0.05%
Key findings
- 01 Significant sebum reduction and 36.6% decrease in scalp flaking after 4 weeks
- 02 No irritation or sensitization in human patch testing
Transparency
Dusting Analysis
Specialized ingredient with clear efficacy data at low concentrations, minimal dusting concerns
The Formula
Formulation
Stability
Heat-sensitive compound requiring addition during cooling phase below 40°C; maintains stability for 4 years under proper storage conditions
Synergies
- niacinamide
- zinc compounds
Conflicts
- strong oxidizing agents
- alkaline pH environments above 8.0
- prolonged UV exposure
Safety
Safety Profile
FDA-recognized flavoring agent with established safety profile; neat form classified as potential irritant but cosmetic dilutions well-tolerated
Your Skin
Skin Compatibility
Our Assessment
Verdict
Well-researched multi-functional ingredient offering proven sebum control and barrier benefits at low, cost-effective concentrations.
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