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BUTYLPARABEN.

Valuable CAS 94-26-8 / FRAGRANCE, PRESERVATIVE

A highly effective antimicrobial preservative that safeguards skincare formulations from bacterial and fungal contamination. Its lipophilic structure makes it particularly potent against a broad spectrum of microorganisms while maintaining excellent stability across various pH conditions.

preservative masking

Science

Penetrates microbial cell membranes through its lipophilic alkyl chain, disrupting membrane transport processes and energy metabolism, ultimately causing cell death through leakage of essential intracellular components.


Research

High confidence
Effective range 0.0125–0.14%
Optimal

0.02%

Key findings

  1. 01 Demonstrated minimum inhibitory concentrations of 0.0125-0.02% against Candida albicans and Staphylococcus aureus
  2. 02 SCCS safety assessment confirmed efficacy and safety at maximum 0.14% concentration for adults

Transparency

Not commonly dusted

As a preservative ingredient with established safety limits and regulatory approval, butylparaben is not typically subject to dusting practices


The Formula

Solubility
Oil
Optimal pH 3 – 8
0 7 14

Stability

Exceptionally stable across pH 3.0-8.0 with optimal performance at pH 3-6. Resistant to heat sterilization and hydrolysis. Water solubility limited to 0.2 g/L but freely soluble in alcohols and oils.

Synergies

  • Other parabens for broad-spectrum preservation
  • Oil-based carrier systems
  • Alcohol-based formulations

Conflicts

  • Non-ionic surfactants (Polysorbate 80)
  • Highly ethoxylated compounds
  • Cellulose derivatives
  • Proteins
  • Lecithin
  • Bentonite and clay minerals

Safety

CIR Status
Safe as used
Max tested
0.14%
Pregnancy
Safe
Sensitization risk Low

EU limits individual use to 0.14% and total paraben combinations to 0.8%. Recent SCCS guidance recommends 0.028% maximum for children's products due to aggregate exposure concerns.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A reliable preservative with proven antimicrobial efficacy at low concentrations, suitable for most skin types except sensitive skin.


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References