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Moumoujus

BUTYLOXEPANONE.

Optional CAS 5579-78-2 / PERFUMING

Butyloxepanone is a macrocyclic lactone primarily utilized in skincare formulations as a fragrance component, delivering a distinctive creamy and buttery olfactory profile. This oil-soluble ingredient demonstrates dual functionality, serving both aesthetic and biocompatibility purposes in cosmetic applications. While its fragrance properties are well-established, emerging research explores its polymer applications in biomedical contexts.

Summary

perfuming

Science

Mechanism of Action

Functions exclusively as a perfuming agent in skincare, where its lactone structure imparts a characteristic milky, buttery scent to formulations through olfactory interaction rather than direct skin biochemical activity.

Research

Clinical Evidence

Medium confidence
Effective range 0.001–1%
Optimal

N/A

Key findings

  1. 01 FDA-recognized safety profile as flavoring agent with creamy/buttery sensory characteristics at 0.001-100 ppm concentrations
  2. 02 Demonstrated high biocompatibility in polymer scaffold applications for medical devices

Transparency

Dusting Analysis

Not commonly dusted

As a fragrance component with established safety profiles, dusting is unlikely at typical use concentrations below 1.0%

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Lactone structure undergoes hydrolytic ring-opening in alkaline conditions above pH 8.0, converting to 6-hydroxydecanoic acid and losing fragrance properties

Conflicts

  • Strong bases
  • Alkaline buffers
  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

EU Cosmetic Ingredients approved and FDA-recognized as safe flavoring agent. GHS classification notes potential irritation in pure concentrated form, but safe at typical fragrance use levels

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Optional

A specialized fragrance ingredient that adds pleasant sensory qualities to formulations without providing direct skin benefits.

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