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BUTYLOCTYL CETEARATE.

Valuable CAS 101227-08-1 / SKIN CONDITIONING - EMOLLIENT

A sophisticated branched-chain ester that delivers exceptional emollient properties while serving as a superior pigment wetter in color cosmetics. This large-molecule ingredient creates an occlusive barrier to prevent moisture loss and enhances the penetration of accompanying active ingredients. Its unique molecular structure provides a distinctive skin feel while maintaining excellent safety across various skin types.

emollient skin conditioning pigment wetting penetration enhancer

Science

Creates an occlusive barrier on the skin surface that effectively reduces transepidermal water loss (TEWL) while its branched-chain architecture provides enhanced pigment dispersion properties and can facilitate the penetration of other formulation actives.


Research

High confidence
Effective range 0.7–97%
Optimal

1.5%

Key findings

  1. 01 Human Repeat Insult Patch Tests across multiple cohorts (156-202 subjects) at 1.5% concentration demonstrated zero sensitization incidents
  2. 02 Pigment wetting efficacy studies at 35% concentration showed superior viscosity reduction compared to standard ester suspensions
  3. 03 Safety evaluation at 0.7% concentration in 198-subject RIPT confirmed non-sensitizing properties

Transparency

Not commonly dusted

Not applicable as this is a functional emollient ingredient rather than an active requiring efficacious dosing


The Formula

Solubility
Oil
Optimal pH 4 – 8.5
0 7 14

Stability

Demonstrates high stability under standard cosmetic manufacturing conditions but susceptible to hydrolysis breakdown under extreme pH conditions

Synergies

  • Pigments and colorants (enhanced dispersion)
  • Active ingredients requiring penetration enhancement

Conflicts

  • Extreme pH environments
  • Strong oxidizing agents
  • Ingredients sensitive to enhanced dermal penetration

Safety

CIR Status
Safe as used
Max tested
97%
Pregnancy
Safe
Sensitization risk Low

CIR Expert Panel approval based on negligible skin penetration due to large molecular size, eliminating systemic toxicity concerns when formulated appropriately


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-researched, multi-functional ingredient that excels in both skincare and color cosmetic applications with excellent safety margins.


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