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Moumoujus

BUTYLOCTANAMIDE MEA.

Valuable / ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING - MISCELLANEOUS, SKIN PROTECTING

A sophisticated endocannabinoid-mimetic fatty acid amide that modulates skin's inflammatory response through targeted cytokine regulation. This Guerbet-based compound excels at barrier restoration while delivering enhanced emollient properties for compromised skin conditions.

Summary

skin conditioning skin protecting antioxidant anti-inflammatory

Science

Mechanism of Action

Works by modulating the skin's endocannabinoid system to suppress inflammatory cytokine production, particularly IL-1α, while optimizing the IL-1RA to IL-1α ratio for reduced sensitivity and enhanced barrier function

Research

Clinical Evidence

High confidence
Effective range 0.5–1%
Optimal

1%

Key findings

  1. 01 Double-blind controlled study at 1.0% demonstrated significant reduction in erythema, improved hydration metrics, and balanced inflammatory markers
  2. 02 Combination study at 0.5% with Palmitamide MEA showed enhanced barrier repair and pruritus reduction in atopic-prone subjects

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Effective concentrations begin at 0.5%, making sub-0.1% concentrations likely ineffective for therapeutic benefits

The Formula

Formulation

Solubility
Oil
Optimal pH 4.5 – 7.5
0 7 14

Stability

Maintains integrity within physiological pH ranges but susceptible to hydrolysis above pH 9

Synergies

  • Palmitamide MEA
  • ceramides
  • cholesterol

Conflicts

  • strong oxidizing agents
  • highly alkaline conditions

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

EU-approved cosmetic ingredient with established safety profile at standard usage concentrations

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A clinically-validated endocannabinoid modulator that delivers measurable anti-inflammatory and barrier-repair benefits for compromised skin.

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