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BUTYLENE GLYCOL PALMITATE.

Valuable CAS 5384-26-9 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A versatile ester that combines the hydrating properties of butylene glycol with the emollient benefits of palmitic acid. This multifunctional ingredient excels as both a skin conditioner and formulation stabilizer, creating smooth, comfortable textures while reducing water loss.

emollient skin conditioning surfactant emulsifying

Science

Works through dual action: fills intercellular gaps between corneocytes to create smoother skin texture, while forming a protective lipophilic barrier that minimizes transepidermal water loss. Its amphiphilic structure enables it to function as a co-emulsifier, stabilizing formulations and enhancing spreadability.


Research

Medium confidence
Effective range 1–10%
Optimal

5%

Key findings

  1. 01 Multi-ingredient formulations containing butylene glycol esters demonstrated 20% improvement in hydration and 24% increase in skin smoothness over 14-28 day period
  2. 02 Non-irritating profile confirmed in 48-hour occluded patch testing across 50 participants

Transparency

Not commonly dusted

Effective concentrations align with typical usage levels, minimal risk of underdosing


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Ester bond susceptible to hydrolysis under extreme pH conditions (below 3 or above 9) and high temperatures, breaking down into constituent butylene glycol and palmitic acid

Synergies

  • Oil-in-water emulsions
  • UV filters (acts as solubilizer)
  • Other emollients

Conflicts

  • Strong oxidizing agents
  • Highly acidic formulations
  • Strongly alkaline environments

Safety

CIR Status
Safe as used
Max tested
40%
Pregnancy
Safe
Sensitization risk Low

CIR Expert Panel confirms safety for alkyl esters including this ingredient; specialty protectant applications may use up to 40% but typical cosmetic concentrations range 1-10%


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-tolerated multifunctional ingredient that effectively combines emollient benefits with formulation stability across all skin types.


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