Science
Mechanism of Action
Works by filling intercellular gaps in the stratum corneum with lipid-like molecules that strengthen the skin barrier, while simultaneously increasing the fluidity of skin's lipid matrix to enhance active ingredient penetration and reduce transepidermal water loss.
Research
Clinical Evidence
Medium confidence1%
Key findings
- 01 Demonstrates barrier-mimicking properties and penetration enhancement at 1-10% concentrations
- 02 Shows preservative-boosting synergy at 0.5-1% levels by improving antimicrobial membrane interaction
Transparency
Dusting Analysis
Typically used at meaningful concentrations for functional benefits rather than marketing purposes
The Formula
Formulation
Stability
Ester structure makes it vulnerable to hydrolysis below pH 3.0 or above pH 9.0, but remains stable in typical emulsion systems
Synergies
- phenoxyethanol
- heavy oils for improved spreadability
Conflicts
- Strong oxidizing agents
- Strong acids
- Strong bases
Safety
Safety Profile
Included in CIR safety assessment of Alkyldiol Alkyl Esters with non-sensitizing and non-irritating profile at typical use levels
Your Skin
Skin Compatibility
Our Assessment
Verdict
A well-researched multifunctional ingredient that effectively combines barrier support with active delivery enhancement at reasonable concentrations.
Related
Similar Ingredients
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References
Sources