Science
Mechanism of Action
Functions as a selective inhibitor of 5α-reductase type 1, the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) in sebaceous glands. By interrupting this hormonal pathway, it reduces sebaceous gland activity and sebum production while providing complementary anti-inflammatory and antioxidant effects.
Research
Clinical Evidence
High confidence1.5%
Transparency
Dusting Analysis
Specialized sebum-regulating ingredient with established clinical efficacy - meaningful concentrations below 0.1% are unlikely to provide therapeutic benefits
The Formula
Formulation
Stability
Lipophilic ester stable up to 75°C, requires antioxidant protection to prevent oxidative degradation
Synergies
- propyl gallate
- other antioxidants
Conflicts
- strong oxidizing agents
- extreme pH formulations
Safety
Safety Profile
CIR-approved under Alkyl Esters category when formulated to be non-irritating, typical use levels 0.5-2.0%
Your Skin
Skin Compatibility
Our Assessment
Verdict
Clinically-proven sebum regulator with robust hormonal mechanism and multi-skin-type compatibility at meaningful concentrations.
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