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BUTYL AVOCADATE.

Valuable / SKIN CONDITIONING

A specialized sebum-regulating ester that targets oil production at its hormonal source by inhibiting the 5α-reductase enzyme. This molecular precision makes it particularly effective for managing excessive oiliness on both face and scalp. Clinical trials demonstrate meaningful reductions in sebum production and greasy appearance within just three weeks of use.

sebum regulator emollient skin conditioning anti-inflammatory

Science

Functions as a selective inhibitor of 5α-reductase type 1, the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) in sebaceous glands. By interrupting this hormonal pathway, it reduces sebaceous gland activity and sebum production while providing complementary anti-inflammatory and antioxidant effects.


Research

High confidence
Effective range 0.5–2%
Optimal

1.5%


Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Specialized sebum-regulating ingredient with established clinical efficacy - meaningful concentrations below 0.1% are unlikely to provide therapeutic benefits


The Formula

Solubility
Oil
Optimal pH 3.8 – 7
0 7 14

Stability

Lipophilic ester stable up to 75°C, requires antioxidant protection to prevent oxidative degradation

Synergies

  • propyl gallate
  • other antioxidants

Conflicts

  • strong oxidizing agents
  • extreme pH formulations

Safety

CIR Status
Safe with restrictions
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

CIR-approved under Alkyl Esters category when formulated to be non-irritating, typical use levels 0.5-2.0%


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Clinically-proven sebum regulator with robust hormonal mechanism and multi-skin-type compatibility at meaningful concentrations.


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