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BUTYL 3-GLYCERYL ASCORBATE.

Valuable CAS 1120360-69-1 / ANTIOXIDANT, HUMECTANT

An advanced vitamin C derivative engineered with enhanced stability and dual-phase compatibility through its unique butyl-glyceryl structure. This amphiphilic compound delivers potent antioxidant protection while offering superior skin penetration compared to traditional L-ascorbic acid. Clinical research demonstrates its effectiveness in combating photo-aging from UVA, blue light, and near-infrared radiation exposure.

antioxidant humectant skin brightening anti-aging

Science

Functions as a multi-pathway antioxidant by neutralizing reactive oxygen species generated from environmental stressors. Simultaneously disrupts melanogenesis through dual mechanisms: suppressing tyrosinase enzyme synthesis and blocking melanin transport proteins (Myosin Va/Kinesin). The glyceryl component provides humectant properties while the butyl chain facilitates deeper dermal penetration.


Research

High confidence
Effective range 1–5%
Optimal

2%


Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Given its proven efficacy at 1-3% concentrations and relative cost as a specialized derivative, meaningful formulations typically contain at least 0.5% to achieve documented benefits.


The Formula

Solubility
Both
Optimal pH 3 – 6
0 7 14

Stability

Exhibits superior oxidative stability compared to L-ascorbic acid with minimal browning. Non-ionic structure maintains gel viscosity and broad emulsifier compatibility.

Synergies

  • Niacinamide
  • Alpha Arbutin
  • Hyaluronic Acid

Conflicts

  • Strong oxidizing agents
  • Strong bases

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Covered under CIR safety assessments for ascorbic acid derivatives (2017, 2024) concluding safety in current usage practices.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically-backed vitamin C derivative offering enhanced stability and penetration with demonstrated efficacy in photo-protection and brightening applications.


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References