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Moumoujus

BUTOXYDIGLYCOL.

Optional CAS 112-34-5 / FRAGRANCE, SOLVENT, VISCOSITY CONTROLLING

A versatile glycol ether that serves multiple roles in skincare formulations as a solvent, viscosity modifier, and penetration enhancer. This ingredient improves the delivery of active compounds into the stratum corneum while helping to mask unpleasant odors from other formula components. With its dual solubility properties and broad pH stability, it's particularly valued in gel-based cleansers and specialized treatment products.

Summary

solvent viscosity controlling penetration enhancer masking agent humectant

Science

Mechanism of Action

Functions as a multifaceted formulation aid that dissolves both water and oil-soluble ingredients while reducing viscosity for improved spreadability. Enhances penetration of active ingredients by facilitating their transport through the skin barrier and provides mild humectant effects to support hydration.

Research

Clinical Evidence

High confidence
Effective range 1–10%
Optimal

9%

Key findings

  1. 01 SCCS safety evaluation confirmed efficacy as solvent in hair formulations up to 9% concentration
  2. 02 Human skin absorption study demonstrated 17.5% penetration of applied dose over 24 hours with minimal metabolic conversion

Transparency

Dusting Analysis

Not commonly dusted

Not typically used as a dusting ingredient due to regulatory restrictions limiting use primarily to hair and nail products

The Formula

Formulation

Solubility
Both
Optimal pH 3 – 9
0 7 14

Stability

Demonstrates excellent stability below 30°C across wide pH range, though requires antioxidant protection to prevent peroxide formation during extended storage

Synergies

  • Active ingredients requiring enhanced penetration
  • Fragrance masking applications

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Aluminum at elevated temperatures

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
10%
Sensitization risk Low

US regulations restrict use primarily to hair and nail products; EU Annex III limits concentration to 9% in hair dyes and prohibits aerosol applications due to inhalation concerns

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Optional

A technically competent formulation aid with regulatory limitations that restrict its broader skincare applications despite demonstrated safety and efficacy.

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References

Sources