Science
Mechanism of Action
Operates through dual-action pathways by inhibiting matrix metalloproteinases (MMP-1, -2, -9, and -10) that degrade collagen, while simultaneously suppressing inflammatory cytokines IL-1β, IL-6, and IL-8. The high concentration of flavonoids butrin and isobutrin provide antioxidant protection against free radical damage and deliver astringent effects for pore refinement.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 UV-B treated keratinocytes showed 32% reduction in IL-1β, 33% decrease in IL-6, and 18% reduction in IL-8 with hydroethanolic extract
- 02 Antioxidant testing at 3mg/mL demonstrated significant DPPH and FRAP activity with 0.685mg/ml phenolic and 0.235mg/ml flavonoid content
Transparency
Dusting Analysis
Specialty botanical extract primarily used in targeted anti-aging and pore-refining formulations rather than as marketing filler
The Formula
Formulation
Stability
Maintains stability in standard emulsion systems and surfactant formulations. Hydroethanolic extraction preserves flavonoid bioactivity. Imparts natural pale yellow to orange coloration in clear bases.
Safety
Safety Profile
EU CosIng approved with extensive traditional Ayurvedic use history. No documented systemic toxicity in topical applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A scientifically-backed botanical with demonstrated anti-inflammatory and collagen-protective properties suitable for comprehensive anti-aging protocols.
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