Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

BURSERA FAGAROIDES WOOD OIL.

Questionable CAS 92874-96-9 / PERFUMING

A bioactive wood oil derived from the Mexican copal tree, rich in potent lignans and monoterpenes that deliver targeted anti-inflammatory and antioxidant benefits. This specialized botanical extract demonstrates significant edema reduction capabilities while providing natural fragrance properties. However, its cytotoxic lignans and sensitizing monoterpenes require careful formulation consideration.

Summary

Anti-inflammatory Antioxidant Perfuming Masking

Science

Mechanism of Action

Functions through dual pathways: bioactive lignans like podophyllotoxin inhibit abnormal cell proliferation by disrupting tubulin polymerization, while monoterpenes including linalool and limonene suppress pro-inflammatory mediators and provide antioxidant protection against oxidative stress.

Research

Clinical Evidence

Medium confidence
Effective range ≤2%
Optimal

N/A

Key findings

  1. 01 Mouse model study showing 51.24% edema inhibition at 1 mg/ear application, demonstrating anti-inflammatory efficacy comparable to indomethacin
  2. 02 Cancer cell line research revealing IC50 of 0.11 µg/mL against PC-3 cells, indicating potent antiproliferative activity from lignan content

Transparency

Dusting Analysis

Not commonly dusted

Limited use as fragrance component with regulated maximum concentration suggests minimal dusting concerns

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Requires protection from light and oxidation through amber container storage in cool conditions

Conflicts

  • PVC materials
  • Strong oxidizing agents
  • Flammable compounds

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
2%
Sensitization risk High

Classified as skin and eye irritant with sensitization potential due to high linalool and limonene content; recognized by FDA as natural flavoring substance under 21 CFR 172.510

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Verdict

Questionable

While demonstrating notable anti-inflammatory efficacy, the high sensitization risk and cytotoxic lignan content make this ingredient suitable only for specialized formulations with proper safety considerations.

Related

Similar Ingredients

Finding similar ingredients…