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Moumoujus

BUPLEURUM FALCATUM LEAF EXTRACT.

Optional CAS 89958-12-3 / SKIN CONDITIONING

A botanical extract derived from the leaves of Bupleurum falcatum, containing bioactive saikosaponins that target fat cell metabolism and skin firmness. This specialized ingredient demonstrates measurable body contouring effects through its ability to stimulate lipolysis while providing complementary anti-inflammatory and antioxidant support.

Summary

skin-conditioning emollient lipolytic agent

Science

Mechanism of Action

Saikosaponins within the extract activate G-proteins and adenylate cyclase pathways in adipocytes, elevating cyclic AMP levels and subsequently triggering hormone-sensitive lipase to break down stored triglycerides into free fatty acids and glycerol, while simultaneously delivering matrix-stabilizing antioxidant effects.

Research

Clinical Evidence

Medium confidence
Effective range 1–3%
Optimal

3%

Key findings

  1. 01 Lipocare™ complex at 3% showed 7.5% thigh circumference reduction and visible cellulite improvement over 28-56 days
  2. 02 Dose-dependent lipolytic activity demonstrated at 1-3% concentrations through adenylate cyclase stimulation

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Given its specialized lipolytic mechanism requiring adequate concentration for adenylate cyclase activation, amounts below 0.5% are likely insufficient for meaningful body contouring benefits.

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Supplied as hydro-glycolic extract with good thermal stability up to 50°C, compatible with gel and O/W emulsion systems

Synergies

  • caffeine
  • carnitine
  • other lipolytic actives

Conflicts

  • strongly alkaline ingredients above pH 8.0

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

Recognized as safe skin-conditioning agent in EU CosIng database and FDA VCRP, typically used up to 5% in commercial formulations

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Optional

A specialized body care ingredient with demonstrated contouring efficacy, though primarily valuable for targeted slimming applications rather than general skincare.

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References

Sources