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Ingredient directory

Bupleurum Falcatum Callus Culture Extract

A biotechnology-derived botanical extract obtained from cell cultures of Bupleurum falcatum, a traditional medicinal plant. This sophisticated ingredient combines skin-firming properties with anti-inflammatory benefits through its high concentration of bioactive saikosaponins. Particularly effective in body care formulations targeting skin texture and firmness improvements.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

skin conditioning astringent soothing antioxidant firming

Science

Activates G-protein receptors on adipocyte membranes to increase intracellular cAMP levels, promoting lipolysis and fat breakdown. The extract's saikosaponins (A, C, D) deliver anti-inflammatory effects while stimulating collagen synthesis through enhanced TGF-beta signaling pathways.


Research

High confidence
Effective range 0.02–5%
Optimal

3%


Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Specialized botanical extract with documented efficacy at meaningful concentrations; unlikely to be used at ineffective trace amounts


The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Heat-sensitive ingredient requiring incorporation below 40°C during cooling phase; requires protection from direct sunlight and high temperatures

Synergies

  • other botanical extracts
  • peptides
  • hyaluronic acid

Conflicts

  • strong oxidizing agents
  • high electrolyte concentrations

Safety

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

EU CosIng database approved for topical use; demonstrated non-cytotoxic in HaCaT cell studies up to 800 µM concentration


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Well-researched botanical with proven firming benefits at practical concentrations, particularly valuable in body care applications.


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