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Moumoujus

BUPLEURUM CHINENSE ROOT EXTRACT.

Valuable CAS 89958-12-3 / ASTRINGENT

A botanical extract derived from Chinese thorowax root that delivers multi-functional skin benefits through bioactive saikosaponins. This traditional Chinese medicine ingredient combines anti-inflammatory, antioxidant, and astringent properties to soothe irritated skin while providing pore-refining effects.

Summary

anti-inflammatory antioxidant astringent soothing lipolytic

Science

Mechanism of Action

Saikosaponins A and D modulate NF-κB inflammatory pathways to reduce cytokine production and PGE2 levels. Simultaneously stimulates adenylate cyclase to increase intracellular cAMP, activating hormone-sensitive lipase for enhanced lipolysis. Provides antioxidant protection by upregulating superoxide dismutase and glutathione peroxidase enzyme activity.

Research

Clinical Evidence

Medium confidence
Effective range 0.1–5%
Optimal

3%

Key findings

  1. 01 Significant reduction in pro-inflammatory cytokines and PGE2 production in human skin cells
  2. 02 Synergistic lipolytic effects with caffeine and coenzyme A, improving skin firmness and cellulite appearance

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Clinical efficacy demonstrated at meaningful concentrations starting from 0.1%, making dusting less common but still possible below this threshold

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 7
0 7 14

Stability

Maintains optimal stability in slightly acidic to neutral pH environments. Commonly formulated as hydro-glycolic extract with butylene glycol for enhanced solubility and emulsion compatibility.

Synergies

  • caffeine
  • coenzyme A
  • butylene glycol

Conflicts

  • strong oxidizing agents
  • extreme pH conditions below 3.0 or above 9.0

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

Listed in Chinese IECIC 2021 with extensive traditional use history in TCM. No formal CIR assessment but considered low-risk based on historical usage patterns.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A well-researched botanical with proven anti-inflammatory and antioxidant benefits, suitable for multiple skin types and concerns.

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