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Ingredient directory

Bulnesia Sarmientoi Extract

Derived from the precious Guaiacwood tree, this botanical extract delivers dual benefits as both a luxurious natural fragrance and a functional skincare active. Rich in sesquiterpene alcohols like bulnesol and guaiol, it provides gentle astringent properties while supporting skin's antioxidant defense systems.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

perfuming soothing antioxidant astringent

Science

Mechanism of Action

Functions through its high concentration of sesquiterpene alcohols (bulnesol and guaiol) which inhibit nitric oxide production and downregulate inflammatory markers including iNOS and COX-2. The astringent properties cause mild contraction of skin tissues and blood vessels, promoting a toning effect while reducing localized swelling.

Research

Clinical Evidence

Medium confidence
Effective range 0.2–1%
Optimal

0.5%

Key findings

  1. 01 In-vitro studies at 18.1-24.7 μg/mL demonstrated significant antioxidant effects and wound healing potential through enhanced cell migration (NIH PMC5133130)
  2. 02 Industry applications at 0.2-1.0% show anti-inflammatory and astringent benefits in cosmetic formulations

Transparency

Dusting Analysis

Not commonly dusted

Not commonly used for dusting due to its primary role as a functional fragrance and specialty active ingredient

The Formula

Formulation

Solubility
Oil
Optimal pH 5 – 6.5
0 7 14

Stability

Highly viscous extract requiring heating or carrier oil dilution for proper incorporation. Functions as a natural fixative for volatile compounds. Maintains stability under standard storage conditions.

Synergies

  • Caprylic/Capric Triglyceride for dilution
  • Other volatile fragrance components as fixative

Conflicts

  • Strong oxidizing agents
  • PVC packaging materials
  • Excessive heat exposure

Safety

Safety Profile

CIR Status
Not reviewed by CIR
Max tested
1%
Sensitization risk Moderate

FDA-listed (UNII) and IFRA-regulated as fragrance component. ECHA classification includes potential sensitizer status (Skin Sens. 1B) due to botanical complexity, though skin irritation evidence is limited.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Optional

A sophisticated multifunctional ingredient that combines luxury fragrance with gentle astringent and antioxidant benefits, though sensitization potential limits broader application.

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