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BUDDLEJA DAVIDII MERISTEM CELL CULTURE.

Valuable CAS 94465-67-5 / SKIN CONDITIONING

Advanced plant stem cell technology derived from butterfly bush meristem tissue, delivering concentrated antioxidants and anti-inflammatory compounds. This biotechnology ingredient demonstrates remarkable efficacy in reducing visible pore size and controlling sebum production while supporting collagen preservation.

antioxidant soothing skin conditioning pore refining sebum control

Science

Functions through multiple pathways including ROS scavenging, IL-8 chemokine inhibition for anti-inflammatory effects, and MMP-1 suppression to prevent collagen breakdown. The active compound verbascoside provides UVA photoprotection and metal chelation properties, while supporting cellular regeneration processes.


Research

High confidence
Effective range 0.5–5%
Optimal

2.5%

Key findings

  1. 01 22-subject study demonstrated 50% pore size reduction in 28 days at 0.5-5% concentration
  2. 02 104 menopausal women showed enhanced collagen synthesis and reduced lipid peroxidation markers
  3. 03 19% sebum reduction achieved within 6 days of application

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Requires meaningful concentrations above 0.5% to deliver clinical benefits; extremely low percentages indicate potential dusting


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Demonstrates high stability in aqueous systems and oil-in-water emulsions. Requires protection from light and heat exposure to preserve phenylpropanoid glycosides integrity.

Synergies

  • hyaluronic acid
  • niacinamide
  • vitamin C

Conflicts

  • strong oxidizing agents
  • formulations with pH above 8.0 or below 4.0

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Excellent safety profile with no documented cases of irritation, burning, or adverse reactions in clinical testing. Natural origin and sustainable production contribute to favorable safety assessment.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Well-researched plant stem cell ingredient with proven efficacy for pore refinement and anti-aging applications across all skin types.


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