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BUDDLEJA DAVIDII LEAF CELL CULTURE EXTRACT.

Valuable CAS 94465-67-5 / SKIN CONDITIONING

A biotechnology-derived extract from butterfly bush leaf cells that delivers concentrated phenylpropanoid glycosides for comprehensive skin protection. This advanced plant cell culture technology provides potent antioxidant defense while simultaneously targeting pigmentation, inflammation, and matrix degradation. The extract represents a sustainable approach to harnessing powerful botanical actives through controlled cellular cultivation.

antioxidant anti-inflammatory skin conditioning brightening anti-aging

Science

Functions through high concentrations of verbascoside and isoverbascoside, which neutralize UV-induced reactive oxygen species, suppress pro-inflammatory IL-8 expression, and inhibit matrix-degrading enzymes including MMPs, collagenase, elastase, and hyaluronidase while blocking tyrosinase activity for pigmentation control.


Research

High confidence
Effective range 0.5–5%
Optimal

2.5%

Key findings

  1. 01 Significant reduction in UV-induced oxidative stress and inflammatory markers with MMP expression inhibition
  2. 02 Potent antityrosinase activity demonstrating hyperpigmentation treatment potential

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Cell culture extracts are expensive to produce, making dusting economically unfavorable; effective concentrations start at 0.5% with proven safety up to 5%


The Formula

Solubility
Water
Optimal pH 3.5 – 6.5
0 7 14

Stability

Excellent stability in aqueous systems and oil-in-water emulsions within acidic to neutral pH ranges; active phenolic compounds degrade rapidly above pH 7.0

Synergies

  • vitamin C
  • niacinamide
  • hyaluronic acid

Conflicts

  • strongly alkaline ingredients
  • potent oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Cytotoxicity studies confirm safety for human keratinocytes and fibroblasts at concentrations up to 200 mg/L; recognized as non-sensitizing botanical extract


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically-backed, multi-functional botanical extract with proven efficacy across UV protection, anti-aging, and brightening applications at reasonable concentrations.


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