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Moumoujus

BUDDLEJA DAVIDII EXTRACT.

Valuable CAS 94465-67-5 / SKIN CONDITIONING

A botanically-derived extract from butterfly bush flowers and stems that delivers concentrated verbascoside, demonstrating superior enzyme inhibition compared to established antioxidants like EGCG. This precision-active ingredient provides comprehensive matrix protection while promoting cellular repair mechanisms through fibroblast activation.

Summary

skin conditioning antioxidant soothing anti-aging wound healing

Science

Mechanism of Action

Functions through verbascoside-mediated inhibition of aging-related enzymes including MMP-1, MMP-2, elastase, and hyaluronidase while simultaneously blocking pro-inflammatory chemokine IL-8 expression and protecting cellular DNA from UVA-induced oxidative damage.

Research

Clinical Evidence

High confidence
Effective range 0.5–5%
Optimal

3%

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Given the demonstrated efficacy at 25 mg/L (0.0025%), concentrations below 0.05% likely represent cosmetic dusting rather than therapeutic dosing.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

Verbascoside exhibits maximum stability at pH 5.0; degradation accelerates significantly above pH 6.5 with complete loss of activity approaching neutral pH within weeks.

Synergies

  • UV filters
  • Hyaluronic acid
  • Niacinamide

Conflicts

  • High pH ingredients (>6.5)
  • Strong oxidizing agents
  • Light-unstable formulations

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Pregnancy
Safe
Sensitization risk Low

Demonstrates no cytotoxic effects up to 500 mg/L in cellular testing; specifically formulated for reactive and sensitive skin applications.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A scientifically-validated botanical with superior enzyme inhibition profiles that delivers measurable anti-aging benefits when formulated at appropriate concentrations.

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