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Moumoujus

BROUSSONETIA KAZINOKI STEM EXTRACT.

Valuable / SKIN CONDITIONING

A Korean botanical extract derived from Paper Mulberry stems, officially recognized by the KFDA as a functional skin-whitening agent. This multi-pathway ingredient combines tyrosinase inhibition, antioxidant protection, and collagenase regulation to address hyperpigmentation while supporting skin matrix integrity.

Summary

Antioxidant Skin brightening Anti-inflammatory Collagenase inhibitor

Science

Mechanism of Action

Functions through three distinct pathways: prenylated flavonoids like Kazinol F competitively inhibit tyrosinase to reduce melanin synthesis, antioxidant compounds neutralize UV-induced reactive oxygen species, and collagenase inhibitors preserve dermal matrix structure to minimize wrinkle formation.

Research

Clinical Evidence

High confidence
Effective range 0.02–1%
Optimal

0.05%

Key findings

  1. 01 87% reduction in inflammatory hTARC secretion at 0.05% concentration
  2. 02 Non-cytotoxic range established at 0.02-0.1% with maintained bioactivity
  3. 03 No irritation or erythema observed in 30 subjects at 1.0% concentration

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.01%
Red flag below
0.005%

Well-established efficacy at low concentrations makes dusting unlikely, with meaningful activity demonstrated above 0.02%

The Formula

Formulation

Solubility
Both
Optimal pH 5 – 7
0 7 14

Stability

Light and heat sensitive; enhanced stability achieved through microemulsions or polymeric microspheres; typically supplied in hydro-glycolic or hydro-ethanolic base

Synergies

  • Vitamin C for enhanced antioxidant activity
  • Niacinamide for complementary brightening effects

Conflicts

  • Strongly acidic formulations below pH 4.0
  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed by CIR
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Widely used in KFDA-approved functional cosmetics; botanical analogs show no sensitization in human repeat insult patch tests

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A clinically-validated multi-functional botanical with proven efficacy in brightening and anti-aging applications at accessible concentrations.

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