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BROMOETHYL PCA.

Valuable CAS - / HUMECTANT

Bromoethyl PCA is a specialized sebum-regulating ingredient that combines hormonal activity with moisture retention properties. This dual-action compound targets excess oil production while simultaneously providing humectant benefits, making it particularly effective for balancing oily and combination skin types.

humectant skin-conditioning sebum-regulating firming

Science

Works by inhibiting 5-alpha reductase enzyme activity, preventing testosterone conversion to DHT within sebaceous glands to reduce sebum production. The PCA component acts as a hygroscopic humectant, while the ester structure supports cutaneous elastic integrity for improved skin firmness.


Research

Medium confidence
Effective range 1–3%
Optimal

2%

Key findings

  1. 01 Significant sebostatic activity with reduced surface sebum levels and improved skin texture over 4-8 weeks

Transparency

Not commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Effective concentrations require minimum 1% for sebostatic activity, making sub-percentage amounts functionally insignificant


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Stable in standard emulsions but prone to ester hydrolysis at pH extremes below 3.0 or above 8.0

Synergies

  • niacinamide
  • zinc compounds
  • salicylic acid

Conflicts

  • Strong oxidizing agents
  • Highly alkaline ingredients
  • Strong inorganic acids

Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

FDA and EU registered with no current Proposition 65 listing, though appeared in broad cosmetic settlement listings


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Effective sebum-regulating ingredient with dual moisturizing benefits, suitable for multiple skin types when used at clinically relevant concentrations.


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