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BRASSICA OLERACEA ITALICA SPROUT EXTRACT.

Valuable CAS - / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

A potent botanical extract derived from young broccoli sprouts, concentrated with sulforaphane compounds that demonstrate superior antioxidant activity compared to mature broccoli. This extract excels at activating cellular defense pathways and protecting against environmental damage, making it particularly valuable for urban skincare routines.

antioxidant skin conditioning soothing astringent

Science

Activates the NRF2 signaling pathway to stimulate endogenous antioxidant production and Phase II detoxification enzymes. Simultaneously upregulates protective keratin proteins (K16 and K17) while inhibiting collagen-degrading matrix metalloproteinases, creating a dual defense against oxidative stress and photoaging.


Research

High confidence
Effective range 1–5%
Optimal

1.3%

Key findings

  1. 01 Johns Hopkins study demonstrated NRF2 activation and protective keratin induction at 500 nmol/mL sulforaphane concentration
  2. 02 2022 research showed 5x greater Nrf2 pathway activation versus mature broccoli at 1.3% concentration
  3. 03 Dose-dependent collagen protection and MMP-1 inhibition observed at 25-100 mg/mL in UVB-stressed fibroblasts

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Given the documented efficacy at 1.3% and stability concerns with sulforaphane, concentrations below 0.1% are likely insufficient for meaningful antioxidant benefit


The Formula

Solubility
Both
Optimal pH 4 – 6.5
0 7 14

Stability

Sulforaphane degrades rapidly above 40°C and requires protection from light and oxygen. Maximum stability achieved in mildly acidic formulations between pH 4.0-6.0.

Synergies

  • Vitamin E
  • Vitamin C
  • Glutathione precursors

Conflicts

  • High heat processing
  • Strong oxidizing agents
  • Alkaline pH environments

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

GRAS status for food use with cosmetic applications typically ranging 1-3%. No specific CIR evaluation available for sprout extract variant.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically-backed antioxidant that delivers superior cellular protection through proven NRF2 activation, though requires careful formulation to maintain stability.


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