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Moumoujus

BRASSICA NAPUS STEM EXTRACT.

Valuable CAS 89958-03-2 (generic) / SKIN CONDITIONING - EMOLLIENT

A bioactive stem cell extract derived from rapeseed (Brassica napus) that functions as a multi-pathway skin brightening agent. This plant-derived ingredient combines tyrosinase inhibition with melanin transport disruption to address hyperpigmentation while providing antioxidant protection through its natural phenolic compounds.

Summary

skin brightening antioxidant skin conditioning

Science

Mechanism of Action

Targets melanogenesis through multiple pathways: inhibits tyrosinase enzyme activity to reduce melanin production, blocks melanosome transfer from melanocytes to keratinocytes, and suppresses Stem Cell Factor (SCF) synthesis which contributes to photoinduced pigmentation. Additionally provides antioxidant protection via phenolic compounds.

Research

Clinical Evidence

Medium confidence
Effective range 3–3%
Optimal

3%

Key findings

  1. 01 28-day human study (n=10) at 3% concentration demonstrated significant age spot lightening and overall skin brightening with twice-daily application
  2. 02 In-vitro melanocyte testing showed 36% reduction in melanin content within 24 hours of exposure

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

Clinical efficacy demonstrated at 3% concentration suggests meaningful inclusion levels are required. Concentrations below 1% likely provide minimal brightening benefits.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Maintains high stability in aqueous formulations within pH 4.0-7.0 range. Protein components may denature below pH 3.0. Store in cool, dark conditions to prevent phenolic compound oxidation.

Conflicts

  • strong oxidizing agents
  • highly acidic formulations (pH < 3.0)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

Brassica napus derivatives have GRAS status and EU CosIng approval for cosmetic use as skin conditioning agents. No specific CIR review available for stem extract variant.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Well-researched brightening ingredient with demonstrated clinical efficacy at 3% concentration and excellent skin compatibility across all types.

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References

Sources