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Moumoujus

BORONOPHENYLALANINE HCL.

Insufficient Data CAS - / NOT REPORTED

Boronophenylalanine HCl is primarily recognized as a boron delivery agent in Boron Neutron Capture Therapy (BNCT) for cancer treatment. Its utility and application in cosmetic skincare formulations are currently unsupported by research.

Summary

Science

Mechanism of Action

In its primary medical role, BPA-HCl functions as a phenylalanine analogue, facilitating selective boron accumulation in tumor cells via L-type amino acid transporters. No mechanism of action related to skin health or cosmetic benefits has been identified.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a hydrochloride salt, Boronophenylalanine HCl is generally water-soluble. The free form of p-boronophenylalanine demonstrates poor water solubility, often requiring complexation for solubilization.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) indicated 'No Reported Uses' for Boronophenylalanine HCl in cosmetics as of 2010, hence it has not undergone safety review for cosmetic application. Its primary use is exclusively in Boron Neutron Capture Therapy.

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