Science
Mechanism of Action
Its mechanism involves scavenging free radicals through phenolic compounds, flavonoids, and polysaccharides. It also reduces pro-inflammatory cytokines like IL-6, IL-1β, and TNFα, and inhibits enzymes such as 5-lipoxygenase, iNOS, and COX-2.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Studies at 0.05% and 0.1% demonstrated significant scavenging of nitric oxide radicals and reduced intracellular ROS production in HepG2 cells.
- 02 At 0.25%, moderate inhibition of the pro-inflammatory enzyme 5-lipoxygenase was observed.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not reviewed this ingredient. While a patent suggests use up to 100%, no official safety assessment or maximum concentration for cosmetic use has been determined by regulatory bodies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Boletus Edulis Whole Plant Extract is a valuable ingredient for its robust antioxidant and anti-inflammatory properties, suitable for all skin types.
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References
Sources