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Moumoujus

BIXA ORELLANA SEED.

Valuable CAS 89957-43-7 / ANTIOXIDANT, SKIN CONDITIONING - EMOLLIENT

This ingredient is a versatile extract known for its potent antioxidant, anti-inflammatory, and antimicrobial properties. It also functions as a skin conditioning agent and a natural cosmetic colorant.

Summary

Antioxidant Cosmetic Colorant Masking Skin Conditioning

Science

Mechanism of Action

Rich in tocotrienols, bixin, and norbixin, it scavenges free radicals and inhibits lipid peroxidation, protecting cells from oxidative stress. Its anti-inflammatory action modulates NF-κB pathways and inhibits COX-2 enzymes, while flavonoids contribute to antimicrobial activity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro, the extract demonstrated 5.5-48.9% free radical scavenging activity.
  2. 02 A tocotrienol component from the seeds reduced UVB-induced cellular damage by 63% compared to UVB-treated cells.
  3. 03 In vitro, it exhibited antibacterial activity against Staphylococcus aureus and Bacillus subtilis.
  4. 04 A lip gloss formulation containing the extract caused no allergic reactions or irritation in a panel of 10 individuals.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 6.5
0 7 14

Stability

Bixin is oil-soluble and norbixin water-soluble. While stable to heat and light, it requires antioxidant protection due to instability in the presence of air oxygen.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally recognized as safe (GRAS) by the FDA for food and cosmetics as a color additive, with a long history of safe use in cosmetics, showing mildness and no significant adverse effects.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Bixa Orellana Seed offers significant antioxidant, anti-inflammatory, and antimicrobial benefits with a good safety profile, making it a valuable addition to diverse skincare formulations.

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