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BISPYRITHIONE.

Valuable CAS 3696-28-4 / ANTIMICROBIAL

Bispyrithione is an antimicrobial compound primarily recognized for its anti-dandruff properties. It demonstrates enhanced efficacy against Malassezia furfur, a yeast commonly associated with dandruff, compared to zinc pyrithione alone.

antimicrobial

Science

Its mechanism involves direct antimicrobial activity, specifically targeting and inhibiting the proliferation of Malassezia furfur. This action helps to restore the microbial balance on the scalp, thereby alleviating dandruff symptoms.


Research

Medium confidence
Effective range 0.01–10%
Optimal

N/A

Key findings

  1. 01 Demonstrated anti-dandruff efficacy against Malassezia furfur within a 0.01-10.0 wt% concentration range (KR20110050899A).
  2. 02 A more specific effective range of 0.25-0.5 wt% was identified for anti-dandruff compositions, showing improved efficacy over zinc pyrithione alone (KR20110050899A).

Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Specific stability and incompatibility data for Bispyrithione are limited. However, related pyrithione compounds, such as Zinc Pyrithione, are unstable in light, oxidizers, and at extreme pH, also incompatible with cationic/non-ionic surfactants and EDTA.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Available safety assessments primarily refer to Zinc Pyrithione (ZPT), indicating a current lack of dedicated safety reviews for Bispyrithione itself.


Your Skin

No Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Bispyrithione is a valuable antimicrobial agent for targeting Malassezia furfur in anti-dandruff applications, though comprehensive formulation and safety data specific to this compound remain limited.


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