Science
Mechanism of Action
Functioning as a dual-action signal and carrier peptide, it optimizes the delivery of copper ions into the dermal layers. Once absorbed, it activates vital enzymes like superoxide dismutase for oxidative protection and lysyl oxidase for the cross-linking of collagen and elastin, while simultaneously signaling fibroblasts to replace damaged proteins with healthy tissue.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 Improvement in skin density and thickness with 0.05% concentration over 8 weeks.
- 02 Acceleration of tissue remodeling and collagen synthesis at 0.1% to 2.0%.
- 03 Enhancement of glycosaminoglycan synthesis and antioxidant defense at 1000 ppm (0.1%).
Transparency
Dusting Analysis
Due to its high cost and distinct blue color, many products include this at symbolic levels (often below 10 ppm) to claim its benefits without achieving the 0.05% threshold required for clinical skin-thickening results.
The Formula
Formulation
Stability
Highly thermolabile; must be integrated during the cool-down phase below 40°C. Maintaining a neutral to slightly acidic pH is vital to prevent complex dissociation and subsequent loss of biological activity.
Synergies
- Hyaluronic acid
- Niacinamide
- Glycerin
Conflicts
- L-Ascorbic Acid
- Chelating agents (Disodium EDTA)
- Strong oxidizers
- Direct acids (AHA/BHA) below pH 4.0
Safety
Safety Profile
Recognized as safe by the CIR Expert Panel when formulated within the 1.0% limit for pure active concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A premier restorative peptide that provides measurable improvements in skin density and architecture when formulated at clinical concentrations.
Related
Similar Ingredients
Finding similar ingredients…