Science
Mechanism of Action
BIS-RETINOYL GEROTINE BIS-HYDROXYSUCCINIMIDE is a retinamide expected to interact with RARs and RXRs, modulating gene expression to boost collagen, enhance skin elasticity, and accelerate cell turnover. The bis-hydroxysuccinimide moiety may facilitate enhanced delivery or controlled release.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Retinoids are inherently unstable; the N-hydroxysuccinimide ester component suggests susceptibility to hydrolysis and deactivation, particularly in basic aqueous environments and at elevated temperatures.
Conflicts
- amines
- basic pH
Safety
Safety Profile
This ingredient is listed in the FDA SRS but lacks specific CIR/SCCS safety assessments. General retinoids can cause irritation like redness or peeling, and are typically advised against during pregnancy.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While its retinoid-like action holds promise for significant skin benefits, specific clinical efficacy and safety data for this particular molecule are currently unavailable.
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