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BIS-RETINOYL GEROTINE BIS-HYDROXYSUCCINIMIDE.

Insufficient Data CAS 666854-47-3 / ANTI-SEBUM, ANTIOXIDANT

This retinamide derivative is anticipated to function as a retinoid, promoting cell renewal and addressing signs of aging, hyperpigmentation, and acne. Its unique structure may offer controlled release within the skin.

Anti-aging Skin elasticity improvement Hyperpigmentation reduction Acne treatment Skin cell turnover acceleration Skin barrier support

Science

BIS-RETINOYL GEROTINE BIS-HYDROXYSUCCINIMIDE is a retinamide expected to interact with RARs and RXRs, modulating gene expression to boost collagen, enhance skin elasticity, and accelerate cell turnover. The bis-hydroxysuccinimide moiety may facilitate enhanced delivery or controlled release.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Retinoids are inherently unstable; the N-hydroxysuccinimide ester component suggests susceptibility to hydrolysis and deactivation, particularly in basic aqueous environments and at elevated temperatures.

Conflicts

  • amines
  • basic pH

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

This ingredient is listed in the FDA SRS but lacks specific CIR/SCCS safety assessments. General retinoids can cause irritation like redness or peeling, and are typically advised against during pregnancy.


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While its retinoid-like action holds promise for significant skin benefits, specific clinical efficacy and safety data for this particular molecule are currently unavailable.


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