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BIS-PCA DIMETHICONE.

Valuable CAS 179005-03-9 / HAIR CONDITIONING

This dimethicone derivative features pyrrolidone carboxylic acid (PCA) groups, acting as a potent humectant and film-forming agent to enhance skin's moisture retention and barrier function.

Humectant Film-forming agent Skin protectant Moisturizer

Science

The PCA component, a natural skin humectant, binds moisture 1.5 times more effectively than glycerin, forming a protective, vapor-permeable surface barrier. Due to its large molecular weight, it remains on the skin's surface, reducing moisture loss and defending against external irritants.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In hair applications, bis-PCA dimethicone demonstrated 1.5 times greater moisture-binding capacity than glycerin, enhancing conditioning and strengthening chemically treated hair by supporting keratin structure.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

While specific optimal pH for skin stability is not explicit, its PCA groups ionize at elevated pH, which enhances affinity to hair. Silicones are generally water-insoluble and often co-formulated with solubilizers.

Synergies

  • volatile amines
  • solubilizers

Safety

CIR Status
Safe as used
Max tested
85%
Sensitization risk Low

The CIR Expert Panel found Dimethicone and related derivatives safe as used in cosmetic formulations when non-irritating, citing unlikely skin absorption due to large molecular weight. It is also FDA-recognized as an OTC skin protectant.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

BIS-PCA Dimethicone is a valuable humectant and barrier-supporting ingredient, providing superior moisture retention and protection for all skin types.


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