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BIS-DIGLYCERYL POLYACYLADIPATE-1.

Valuable CAS 222722-06-7 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

A high-performance, vegan-friendly lipid designed to replicate the barrier-protecting properties of lanolin without the allergen risk. This multi-functional emollient excels at moisture retention and smoothing the skin's surface architecture, making it a cornerstone for advanced barrier repair formulas.

Emollient Skin Conditioning Agent Film Former Moisture Reservoir

Science

Functioning as a semi-occlusive film-former, it creates a substantive breathable shield on the epidermis to minimize trans-epidermal water loss (TEWL). Its high hygroscopic nature allows it to bind 1.7 times its weight in water, acting as a reservoir that continuously hydrates the skin while filling in micro-ridges for a refined texture.


Research

High confidence
Effective range 1–36%
Optimal

5%

Key findings

  1. 01 Demonstrated a water-binding capacity of 170%, significantly outperforming standard synthetic emollients in hydration efficiency.
  2. 02 A clinical study utilizing this lipid within a peptide matrix showed an 11% reduction in fine line visibility and a 12% improvement in skin elasticity over a 28-day period.
  3. 03 Safety testing via HRIPT confirmed no irritation or sensitization even at concentrations as high as 36%.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

Due to its high cost compared to basic mineral oils or petrolatum, it is often replaced by cheaper alternatives. While it is effective even at low levels, a concentration below 1% in a 'barrier repair' product may indicate it is being used for marketing claims rather than functional efficacy.


The Formula

Solubility
Oil
Optimal pH 4.5 – 7
0 7 14

Stability

Exhibits excellent oxidative stability and does not undergo rancidity. Its hygroscopic nature means it must be stored away from moisture to prevent turbidity.

Synergies

  • Peptides
  • Ceramides
  • Hyaluronic Acid

Conflicts

  • Extreme pH environments (below 4.5 or above 7.0)
  • Highly anionic surfactant systems

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Recognized as a safe, non-sensitizing ingredient suitable for delicate areas including the lips and eye contour.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A superior, biocompatible emollient that offers exceptional hydration and barrier support for dry and aging skin profiles.


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